BDBM50079412 (NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2::Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2::Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2(Neurokinin B)::CHEMBL437797::NKB::Neurokinin B
SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(N)=O
InChI Key InChIKey=NHXYSAFTNPANFK-HDMCBQFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50079412
Affinity DataKi: 16nMAssay Description:Displacement of [125I]NKA from human NK2R expressed in CHO cell membranes after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:The compound was tested for competition binding with [3H]NKA against the CHO cells from cloned human Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Competitive inhibition of [125I]NKA binding to hamster urinary bladder Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:In vitro agonistic activity against tachykinin receptor 2 of rat colon muscularis mucosae.More data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibitory activity against human Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against Tachykinin receptor 2 in membranes prepared from hamster urinary bladder labeled with [125 I] NKAMore data for this Ligand-Target Pair